Crafting

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To enter the crafting screen, right click on a character avatar and select 'Item Workshop'.

Depending on what kind of combination you are going for, you may need a character with the Mephistics skill (poisoning weapons) or the Alchemistry skill, which doubles as a spellcasting skill for the Thaumaturge. Both Mephistics and Alchemistry are Mental Skills that several classes have.

Here are some of the items you can combine in crafting:

Mephistics:

Needle darts + Poison Dust = Poisoned Dart

Gauche + Poison Dust = Poisoned Dagger

Poison Dust + Hunting Knife = Poisoned Dagger

Poison Dust + Barbed Arrow = Poisoned Arrow

Alchemy:

Cure light wounds + Cure Lt. Condition = Cure heavy wounds

Nematic dust + Mandrake root = Paralysis Dust

Piligrim Tea + Lithe Liquer = Stone to Flesh

Cherry wine + Lithe liquer = Crimson Ambrosia

Lithe liquer + Cure Lt. Condition = Cure Paralysis

Cure heavy wounds + Cherry wine = neutralize poison

Cure heavy wounds + Arsenic = Cure Paralysis

Cure heavy wounds + Amaranth = Stone to Flesh

Cure heavy wounds + nightshade = Remove Curse

Burning oil + draconic bile = Super Burning Oil

Burning oil + stink bomb = super burning oil

Burning oil + neutral medium = True seeing

Burning oil + cure light condition = neutralize poison

Paralysis Dust + Poison Dust = Medusa Dust

Paralysis Dust + Hemlock = Viper Ashes

Centaur Bane + Dracaena Petals = Remove Curse

Zephyr Cola + Cure lt. condition = Stone to Flesh

Zephyr Cola + Amaranth = Cure Paralysis

Zephyr Cola + Black Lotus = neutralize poison

Zephyr Cola + Burning oil = super burning oil

Valerian Root + archangelicus = bag of sparkles

Valerian Root + blood tamarinde = neutralize poison

Valerian Root + bitter tuber = Cure Paralysis

Valerian Root + black rose = Cure Heavy Wounds

Dracaena Petals + Arsenic = Poison Dust

Woundwort + Amaranth = Bag of Slumber

Woundwort + Cure lt. wounds = Cure Heavy Wounds

Woundwort + Cure lt. condition = Cure Paralysis

Black Lotus + Arsenic = Poison Dust

Harpy Crown + Blood Tamarinde = Blink

Arsenic + Grave Moss = Wolfbane

Arsenic + Coffin Orchid = Sleep Sand

Whiterot + Peckle plantain = Stink Bomb

Vial of Essence Spirit + Vial of Night Mist = Prematter Ectoplasm

Vial of Night Mist + Pipes Majestyl = Prematter Ectoplasm

Notes

Keep in mind: The order listed above matters (Primary + Secondary), you can put them in any order, but you need select the Primary item to merge or apply poison.

When you click an item on the bench, it tells you what skill you need to mix it and the level of the skill. So far I have seen either Alchemistry or Mephistics (Alchemistry is much more common). I have not found any items that need Nature Lore or Metallurgy, but I have some confidence that the latter exist. Cleve mentioned that a lot of the metallurgy tables are missing, but not all.

Keep in mind that if you click on an item and it says "unknown", it does not neccessarly mean this item cannot be combined with anything. It can also mean that it is not the "primary" ingredient of any recipe but it could be a "secondary". For example, if you click on a Cure Light Condition potion on the bench, it is marked as "unknown". But it is a secondary component to mix with Burning Oil or with Cure Light Wounds.

Combining items, may give you multiple stack of it (1 Poison Dust + 1 Barbed Arrow, can give you arround 20+ Poisoned Arrows)